Acetyl hexapeptide-37
Cosmetic ingredientCosmetic signal peptide
Also known as: Diffuporine, Acetyl Hexapeptide 37
Early evidence, mostly unproven in humans
- Regulatory standing. Cosmetic ingredient, not regulated as a drug
- Limited human data. Some human data exists, not conclusive
- Registered human trials. 2 registered studies on ClinicalTrials.gov
- 1 cited source. Includes primary / regulatory sources
Computed with the same four public criteria as every profile. The human-evidence grade on an indexed profile is set automatically and may change when it is hand-reviewed. It is not a safety score, not a purity rating, and not medical advice, and not a claim that this compound treats, cures, or prevents any condition.
What it is
Acetyl hexapeptide-37, sold under the trade name Diffuporine, is a synthetic short peptide used as an ingredient in skin care products. Manufacturer materials describe it as intended to support skin hydration by promoting aquaporin-3, a water channel protein in the skin, though this mechanism comes mainly from supplier lab data.
What the evidence shows
It is a cosmetic ingredient and is not FDA-approved for any medical use. Two registered human studies are listed, but no peer-reviewed publications were found, so independent human evidence for its effects is very thin.
Key facts
Registered human trials
Live from ClinicalTrials.gov, refreshed daily.
Sources
- PubChem compound record (CID 169450578)
- Registered trials on ClinicalTrials.gov
- Published papers on Europe PMC
Risks, side effects and study doses are only published on hand-reviewed profiles. Want this one reviewed, or spotted something wrong? Tell us.