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A cosmetic ingredient, not regulated or approved as a drug. This page is educational information only, not medical advice.
IndexedBuilt automatically from public databases on 2026-09-30. Not yet hand-reviewed by PLOBT.How this works →

Acetyl tetrapeptide-3

Cosmetic ingredient

Cosmetic signal peptide

Also known as: Capixyl, Folixyl, Kollaren 6, Acetyl tetrapeptide-1, Uxi hair growth peptide, Ac-lys-gly-his-lys-NH2, AcetylTetrapeptide-3, Acetyl tetrapeptide-3?

Evidence score
23/ 100
Thin evidence

Very thin human evidence

  • Regulatory standing. Cosmetic ingredient, not regulated as a drug
  • Animal / preclinical only. Evidence is largely animal or in-vitro
  • No registered human trials. Nothing registered on ClinicalTrials.gov
  • 1 cited source. Includes primary / regulatory sources

Computed with the same four public criteria as every profile. The human-evidence grade on an indexed profile is set automatically and may change when it is hand-reviewed. It is not a safety score, not a purity rating, and not medical advice, and not a claim that this compound treats, cures, or prevents any condition.

What it is

Acetyl tetrapeptide-3 is a short synthetic peptide used as an ingredient in cosmetic hair and scalp products, often sold as part of the blend known as Capixyl. It is thought to act on the extracellular matrix around hair follicles, with proposed effects on follicle anchoring and reduced inflammation, based largely on manufacturer and laboratory data.

What the evidence shows

Automatic summaryAnimal / preclinical

It is not FDA-approved for any condition, and no registered human clinical trials were found, with only one published paper identified. Claims about hair growth or reduced hair loss rest mainly on lab studies and small manufacturer-sponsored reports, so benefits in humans are not established.

Key facts

Molecular formula
C22H39N9O5
Molecular weight
509.6 g/mol

Registered human trials

Live from ClinicalTrials.gov, refreshed daily.

0registered studies
Nonemost advanced phase
0completed (sample)
0recruiting (sample)

Published literature

Live from Europe PMC. This is how much has been published, not how much is proven in humans.

1papers referencing Acetyl tetrapeptide-3

An Herbal Extract Combination (Biochanin A, Acetyl tetrapeptide-3, and Ginseng Extracts) versus 3% Minoxidil Solution for the Treatment of Androgenetic Alopecia: A 24-week, Prospective, Randomized, Triple-blind, Controlled Trial.

J Clin Aesthet Dermatol2020

Sources

Risks, side effects and study doses are only published on hand-reviewed profiles. Want this one reviewed, or spotted something wrong? Tell us.