Caprooyl tetrapeptide-3
Cosmetic ingredientCosmetic signal peptide
Also known as: ChroNOline
Very thin human evidence
- Regulatory standing. Cosmetic ingredient, not regulated as a drug
- Animal / preclinical only. Evidence is largely animal or in-vitro
- No registered human trials. Nothing registered on ClinicalTrials.gov
- No sources. Nothing cited to verify
Computed with the same four public criteria as every profile. The human-evidence grade on an indexed profile is set automatically and may change when it is hand-reviewed. It is not a safety score, not a purity rating, and not medical advice, and not a claim that this compound treats, cures, or prevents any condition.
What it is
Caprooyl tetrapeptide-3, sold under the trade name ChroNOline, is a short synthetic peptide with a caproic acid (fatty acid) chain attached, used as an ingredient in skin care products. It is marketed as a signaling peptide thought to support proteins in the skin's supporting layer, such as those linking the outer and inner skin layers, though this mechanism is described mainly in manufacturer materials.
What the evidence shows
There are no registered human clinical trials and only one published paper, so claims about skin firmness or wrinkle reduction rest largely on supplier data and are not independently established. It is regulated as a cosmetic ingredient, not an FDA-approved drug.
Sources
Risks, side effects and study doses are only published on hand-reviewed profiles. Want this one reviewed, or spotted something wrong? Tell us.