Collagen peptides
SupplementDietary protein supplement
Also known as: hydrolyzed collagen, collagen hydrolysate
Early evidence, mostly unproven in humans
- Regulatory standing. Sold as a supplement, not an approved drug
- Limited human data. Some human data exists, not conclusive
- Registered human trials. 48 registered studies on ClinicalTrials.gov
- No sources. Nothing cited to verify
Computed with the same four public criteria as every profile. The human-evidence grade on an indexed profile is set automatically and may change when it is hand-reviewed. It is not a safety score, not a purity rating, and not medical advice, and not a claim that this compound treats, cures, or prevents any condition.
What it is
Collagen peptides are short protein fragments made by breaking down animal collagen, usually from bovine, porcine, or fish sources, through hydrolysis. They are sold as dietary supplements, not approved drugs. After digestion, some small collagen-derived peptides and amino acids reach the bloodstream, and it is thought they may act as building blocks or signals for tissues such as skin, cartilage, and bone.
What the evidence shows
There are about 46 registered human trials and a large published literature, with some randomized studies reporting modest changes in skin hydration or elasticity and joint discomfort, but many are small, short, or industry funded, and results are mixed. No health benefit is established to the level of FDA approval, and long-term outcomes remain unclear.
Registered human trials
Live from ClinicalTrials.gov, refreshed daily.
Predictives Factors of Cardiac Resynchronization Therapy: a Multimodal Analysis Using 2D Speckle Tracking Echocardiography Coupled With MIBG Myocardial Scintigraphy and Heart Failure Biomarkers
Impact of the Source and Food Matrices on the Bioavailability of Peptan® (Collagen Peptides) in Healthy Subjects
Evaluation of the Skin-Beautifying Effects of Collagen Drinks
Hydrolyzed Collagen As A Host Modulation Agent in Non-Surgical Periodontal Treatment
Published literature
Live from Europe PMC. This is how much has been published, not how much is proven in humans.
Characterization of collagen peptides by sodium dodecylsulfate-polyacrylamide electrophoresis.
The inflammophilic character of the periodontitis-associated microbiota.
Species identification by analysis of bone collagen using matrix-assisted laser desorption/ionisation time-of-flight mass spectrometry.
Identification of food-derived collagen peptides in human blood after oral ingestion of gelatin hydrolysates.
Sources
Risks, side effects and study doses are only published on hand-reviewed profiles. Want this one reviewed, or spotted something wrong? Tell us.