Epithalon
NOT FDA APPROVEDLongevity peptide
Also known as: Epitalon, AEDG peptide
Not FDA approved. Sold as a research chemical, labelled not for human consumption.
Very thin human evidence
- Regulatory standing. Sold as a research chemical, not approved
- Animal / preclinical only. Evidence is largely animal or in-vitro
- No registered human trials. Nothing registered on ClinicalTrials.gov
- 1 cited source. Cited references provided
A read on the weight of evidence and regulatory standing behind this compound. It is not a safety score, not a purity or quality rating, and not medical advice. It is not a claim that this compound treats, cures, or prevents any condition, and not an endorsement or a recommendation to buy or use it. A low score means the evidence is thin — not that a product is unsafe; a high score means the evidence is strong — not that anyone should take it. PLOBT is independent and takes no money from any vendor; no company can pay to change this score.
Mostly speculative. The telomerase and lifespan claims come from older Russian research that has not been independently replicated to Western standards. Of the popular 'longevity' peptides, this one has the weakest modern evidence. Be skeptical.
What it is
A short synthetic peptide claimed to activate telomerase and influence the pineal gland and circadian regulation.
What the research says
Claims rest largely on older Russian studies; independent replication is lacking.
Published literature
Live from Europe PMC. Peer-reviewed papers discussing Epithalon in their title or abstract, most-cited first. This is how much has been published — not how much is proven in humans. It counts landmark trials, animal studies and reviews alike.
Penetration of short fluorescence-labeled peptides into the nucleus in HeLa cells and in vitro specific interaction of the peptides with deoxyribooligonucleotides and DNA.
Epithalon peptide induces telomerase activity and telomere elongation in human somatic cells.
Studies of the effects of Vilon and Epithalon on gene expression in mouse heart using DNA-microarray technology.
Peptide promotes overcoming of the division limit in human somatic cell.
Registered human trials
Live from ClinicalTrials.gov, the US NIH registry of human studies, refreshed daily. Counts studies where Epithalon is the intervention being tested.
No interventional studies for Epithalon are registered on ClinicalTrials.gov. That is not proof it is unsafe or useless, but it means the human evidence here does not come from registered clinical trials, the exact gap the marketing tends to hide.
FDA recalls & enforcement
Epithalon has no FDA recall or drug record at all — because it is not an FDA-regulated drug. That absence is not a safety signal. It means this compound is sold outside the system that inspects, tracks and recalls unsafe products in the first place.
Source: openFDA drug enforcement.
What people log it for
Descriptive, based on what users track. Not an endorsement or a suggested use.
Risks & unknowns
- Evidence base is weak and largely unreplicated.
- No meaningful long-term human safety data.
Doses reported in studies & protocols
No established clinical dose. This is not a recommendation.
Purity reality
A COA is the only way to confirm content.
None yet. PLOBT does not publish invented purity numbers. Real third-party COA data, mapped to vendor and batch, is in development — and it is the one thing we refuse to fake.
Sources
We cite peer-reviewed journals, PubMed/PMC, FDA and university sources, not vendor marketing.