GHRP-2
Not FDA approvedGrowth hormone secretagogue
Also known as: pralmorelin, Pralmorelin, KP-102, pralmorelina, pralmoreline, KP 102, Ala-beta-Nal-Ala-Trp-Phe-Lys-NH2, pralmorelinum
Early evidence, mostly unproven in humans
- Regulatory standing. Sold as a research chemical, not approved
- Limited human data. Some human data exists, not conclusive
- No registered human trials. Nothing registered on ClinicalTrials.gov
- 1 cited source. Includes primary / regulatory sources
Computed with the same four public criteria as every profile. The human-evidence grade on an indexed profile is set automatically and may change when it is hand-reviewed. It is not a safety score, not a purity rating, and not medical advice, and not a claim that this compound treats, cures, or prevents any condition.
What it is
GHRP-2, also called pralmorelin, is a synthetic peptide in the growth hormone releasing peptide family. It is thought to act on the ghrelin receptor (growth hormone secretagogue receptor) in the pituitary and brain, triggering release of growth hormone and often raising appetite, cortisol, and prolactin as well.
What the evidence shows
Older published human studies show it can acutely raise growth hormone levels, and it has been used in Japan as a diagnostic test agent, but it is not FDA-approved and no registered human trials are listed. Long-term benefits and safety for any health or performance outcome have not been established in humans.
Key facts
Registered human trials
Live from ClinicalTrials.gov, refreshed daily.
Published literature
Live from Europe PMC. This is how much has been published, not how much is proven in humans.
Reactivation of pituitary hormone release and metabolic improvement by infusion of growth hormone-releasing peptide and thyrotropin-releasing hormone in patients with protracted critical illness.
Neuroendocrinology of prolonged critical illness: effects of exogenous thyrotropin-releasing hormone and its combination with growth hormone secretagogues.
Anti-inflammatory effect of the ghrelin agonist growth hormone-releasing peptide-2 (GHRP-2) in arthritic rats.
Growth hormone-releasing peptides.
Sources
- PubChem compound record (CID 6918245)
- Registered trials on ClinicalTrials.gov
- Published papers on Europe PMC
Risks, side effects and study doses are only published on hand-reviewed profiles. Want this one reviewed, or spotted something wrong? Tell us.