Human chorionic gonadotropin
FDA approved · RxGonadotropin glycoprotein hormone
Also known as: hCG, Pregnyl, Novarel, Ovidrel
Strong, human-grade evidence
- Regulatory standing. FDA-approved prescription medicine
- Human trials. Backed by controlled human studies
- Registered human trials. 411 registered studies on ClinicalTrials.gov, most advanced Phase 4
- No sources. Nothing cited to verify
Computed with the same four public criteria as every profile. The human-evidence grade on an indexed profile is set automatically and may change when it is hand-reviewed. It is not a safety score, not a purity rating, and not medical advice, and not a claim that this compound treats, cures, or prevents any condition.
What it is
Human chorionic gonadotropin (hCG) is a glycoprotein hormone produced naturally by the placenta during pregnancy, and pharmaceutical versions are extracted from urine or made recombinantly. It acts on the same receptor as luteinizing hormone (LH), signaling the ovaries to release an egg and support the corpus luteum, and signaling the testes to produce testosterone.
What the evidence shows
hCG products such as Pregnyl, Novarel, and Ovidrel are prescription drugs approved for inducing ovulation in certain infertility treatments, and some formulations are approved for prepubertal cryptorchidism and hypogonadotropic hypogonadism in males, supported by hundreds of registered trials reaching Phase 4. It is not established as effective for weight loss, and product labeling states it has no demonstrated benefit for that use.
Registered human trials
Live from ClinicalTrials.gov, refreshed daily.
Dual Trigger" in IVF Patients at High Risk of Ovarian Hyper Stimulation Syndrome
Comapring Luteal Phase Support in IVF Patients Who Are at High Risk for Developing OHSS
IVF Clinical Trial of Two Different Treatment Protocols.
Efficacy and Safety of Pulsatile Gonadotropin Releasing Hormone Pump Treatment in Patients With Idiopathic Hypogonadotropic Hypogonadism
Published literature
Live from Europe PMC. This is how much has been published, not how much is proven in humans.
Incidence of early loss of pregnancy.
International Germ Cell Consensus Classification: a prognostic factor-based staging system for metastatic germ cell cancers. International Germ Cell Cancer Collaborative Group.
First-trimester or second-trimester screening, or both, for Down's syndrome.
Low O2 tensions and the prevention of differentiation of hES cells.
Sources
Risks, side effects and study doses are only published on hand-reviewed profiles. Want this one reviewed, or spotted something wrong? Tell us.