Insulin human
FDA approved · RxPeptide hormone, insulin
Also known as: Humulin, Novolin, Afrezza, Humulin R, Humulin R U-500 Kwikpen, Humulin N, Myxredlin, Humulin 70/30, Humulin 70/30 Kwikpen, Insulin (human)
Strong, human-grade evidence
- Regulatory standing. FDA-approved prescription medicine
- Human trials. Backed by controlled human studies
- Registered human trials. 8219 registered studies on ClinicalTrials.gov, most advanced Phase 4
- 2 cited sources. Includes primary / regulatory sources
Computed with the same four public criteria as every profile. The human-evidence grade on an indexed profile is set automatically and may change when it is hand-reviewed. It is not a safety score, not a purity rating, and not medical advice, and not a claim that this compound treats, cures, or prevents any condition.
What it is
Insulin human is a laboratory-made version of the hormone the pancreas produces to regulate blood sugar, identical in amino acid sequence to natural human insulin. It acts on insulin receptors in muscle, fat, and liver to promote glucose uptake and storage and to reduce glucose production by the liver. It is sold in several forms, including regular (short-acting), NPH (intermediate-acting), premixed, and an inhaled powder (Afrezza).
What the evidence shows
Insulin human is FDA-approved for improving blood sugar control in people with diabetes mellitus, supported by decades of clinical use and thousands of registered human trials. It is a prescription medicine, and its known risks, especially low blood sugar, are well documented.
Key facts
Registered human trials
Live from ClinicalTrials.gov, refreshed daily.
Can Enhanced Glycemic Control in Type II Diabetics Improve Myocardial Protection During Coronary Artery Bypass Grafting?
Observational Study to Evaluate the Effectiveness and Safety Study of the Dexcom G4™ Continuous Glucose Monitoring System
Feasibility Study of the Solo™ Insulin Pump
Impact of Acute Exercise on Vascular Insulin Sensitivity in Metabolic Syndrome
Published literature
Live from Europe PMC. This is how much has been published, not how much is proven in humans.
Intranasal insulin improves memory in humans.
Pancreas regeneration.
Long-acting insulin analogues versus NPH insulin (human isophane insulin) for type 2 diabetes mellitus.
Islet amyloid: a complication of islet dysfunction or an aetiological factor in Type 2 diabetes?
Sources
- PubChem compound record (CID 118984375)
- FDA drug label on DailyMed
- Registered trials on ClinicalTrials.gov
- Published papers on Europe PMC
Risks, side effects and study doses are only published on hand-reviewed profiles. Want this one reviewed, or spotted something wrong? Tell us.