Menotropins
FDA approved · RxGonadotropin fertility hormone
Also known as: hMG, Menopur
Strong, human-grade evidence
- Regulatory standing. FDA-approved prescription medicine
- Human trials. Backed by controlled human studies
- Registered human trials. 172 registered studies on ClinicalTrials.gov, most advanced Phase 4
- 1 cited source. Includes primary / regulatory sources
Computed with the same four public criteria as every profile. The human-evidence grade on an indexed profile is set automatically and may change when it is hand-reviewed. It is not a safety score, not a purity rating, and not medical advice, and not a claim that this compound treats, cures, or prevents any condition.
What it is
Menotropins, also called human menopausal gonadotropin (hMG), is a purified mix of follicle-stimulating hormone (FSH) and luteinizing hormone (LH) activity extracted from the urine of postmenopausal women. These hormones act on the ovaries to stimulate the growth and maturation of multiple follicles. It is sold in the US under the brand name Menopur.
What the evidence shows
Menotropins is FDA approved for stimulating the development of multiple follicles in women undergoing assisted reproductive technology such as IVF, and it has been studied in about 170 registered human trials up to Phase 4. Its effects and risks, including ovarian hyperstimulation syndrome and multiple pregnancy, are well characterized in that clinical setting.
Key facts
Registered human trials
Live from ClinicalTrials.gov, refreshed daily.
Testosterone TRANSdermal Gel for Poor Ovarian Responders Trial
Endometrial Injury and IVF Outcome Parameters in Patients With Failed IVF Cycles
Predictors of Ovarian Reserve in Infertile Women
Comparative Study on the Efficacy of Ovarian Stimulation Protocols on the Success Rate of ICSI in Female Infertility
Published literature
Live from Europe PMC. This is how much has been published, not how much is proven in humans.
Plasma estradiol is superior to ultrasound and urinary estriol glucuronide as a predictor of ovarian hyperstimulation during induction of ovulation with menotropins.
Luteinzing hormone activity in menotropins optimizes folliculogenesis and treatment in controlled ovarian stimulation.
Pergonal (menotropins): a summary of clinical experience in the induction of ovulation and pregnancy.
The impact of long-term gonadotropin-releasing hormone analogue treatment on preclinical abortions in patients with severe endometriosis undergoing in vitro fertilization-embryo transfer.
Sources
Risks, side effects and study doses are only published on hand-reviewed profiles. Want this one reviewed, or spotted something wrong? Tell us.