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A cosmetic ingredient, not regulated or approved as a drug. This page is educational information only, not medical advice.
IndexedBuilt automatically from public databases on 2026-09-30. Not yet hand-reviewed by PLOBT.How this works →

Palmitoyl tetrapeptide-10

Cosmetic ingredient

Cosmetic signal peptide

Evidence score
16/ 100
Thin evidence

Very thin human evidence

  • Regulatory standing. Cosmetic ingredient, not regulated as a drug
  • Animal / preclinical only. Evidence is largely animal or in-vitro
  • No registered human trials. Nothing registered on ClinicalTrials.gov
  • No sources. Nothing cited to verify

Computed with the same four public criteria as every profile. The human-evidence grade on an indexed profile is set automatically and may change when it is hand-reviewed. It is not a safety score, not a purity rating, and not medical advice, and not a claim that this compound treats, cures, or prevents any condition.

What it is

Palmitoyl tetrapeptide-10 is a short synthetic peptide of four amino acids attached to a palmitic acid fatty chain, which is meant to help it penetrate the skin. It is used as an ingredient in skin care products, where manufacturers describe it as supporting skin barrier or skin clarity, but its exact mechanism in human skin is not well characterized in independent literature.

What the evidence shows

Automatic summaryAnimal / preclinical

There are no registered human clinical trials and only one published paper was identified, so claims about its effects on skin rest mainly on manufacturer or lab data. Whether it produces meaningful benefits in people is unclear.

This name is shared with unrelated compounds in public databases, so trial and paper counts are not shown here, and the evidence score counts no registered trials. Treat this profile as a starting point only.

Sources

Risks, side effects and study doses are only published on hand-reviewed profiles. Want this one reviewed, or spotted something wrong? Tell us.