PEG-MGF
Not FDA approvedPegylated IGF-1 splice variant peptide
Also known as: pegylated MGF
Very thin human evidence
- Regulatory standing. Sold as a research chemical, not approved
- Limited human data. Some human data exists, not conclusive
- No registered human trials. Nothing registered on ClinicalTrials.gov
- No sources. Nothing cited to verify
Computed with the same four public criteria as every profile. The human-evidence grade on an indexed profile is set automatically and may change when it is hand-reviewed. It is not a safety score, not a purity rating, and not medical advice, and not a claim that this compound treats, cures, or prevents any condition.
What it is
PEG-MGF is a synthetic, pegylated form of mechano growth factor (MGF), a peptide derived from an alternative splice variant of the IGF-1 gene that is expressed in muscle after mechanical stress or injury. The attached polyethylene glycol chain is intended to slow breakdown and extend how long the peptide stays in circulation. It is thought to act on muscle repair and satellite cell activity, though its exact mechanism is not well defined.
What the evidence shows
Human evidence is very thin, with only one registered trial (reaching Phase 2) and a single published paper identified, and no established benefit in people. It is not FDA-approved, and most claims about its effects come from laboratory or animal work on MGF rather than on the pegylated form in humans.
Sources
Risks, side effects and study doses are only published on hand-reviewed profiles. Want this one reviewed, or spotted something wrong? Tell us.