Sardine peptides
SupplementFood-derived bioactive peptide
Also known as: valyl-tyrosine
Very thin human evidence
- Regulatory standing. Sold as a supplement, not an approved drug
- Limited human data. Some human data exists, not conclusive
- No registered human trials. Nothing registered on ClinicalTrials.gov
- No sources. Nothing cited to verify
Computed with the same four public criteria as every profile. The human-evidence grade on an indexed profile is set automatically and may change when it is hand-reviewed. It is not a safety score, not a purity rating, and not medical advice, and not a claim that this compound treats, cures, or prevents any condition.
What it is
Sardine peptides are short protein fragments produced by enzymatic breakdown of sardine muscle, with valyl-tyrosine (Val-Tyr) often cited as a key component. They are sold as dietary supplement ingredients and are thought to act by mildly inhibiting angiotensin-converting enzyme (ACE), which plays a role in blood pressure regulation.
What the evidence shows
A small number of human studies, mostly from Japan, have looked at blood pressure effects, but the evidence is limited, with only one registered human trial and few published papers. It is not FDA-approved for any condition, and whether it has meaningful clinical effects remains unclear.
Registered human trials
Live from ClinicalTrials.gov, refreshed daily.
Published literature
Live from Europe PMC. This is how much has been published, not how much is proven in humans.
Sardine peptide with angiotensin I-converting enzyme inhibitory activity improves glucose tolerance in stroke-prone spontaneously hypertensive rats.
Combinative effect of sardine peptides and quercetin alleviates hypertension through inhibition of angiotensin I converting enzyme activity and inflammation.
[Antihypertensive effect and safety evaluation of vegetable drink with peptides derived from sardine protein hydrolysates on mild hypertensive, high-normal and normal blood pressure subjects].
Scientific Opinion on the safety of 'sardine Peptide Product'.
Sources
Risks, side effects and study doses are only published on hand-reviewed profiles. Want this one reviewed, or spotted something wrong? Tell us.