Somatropin
FDA approved · RxRecombinant human growth hormone
Also known as: HGH, growth hormone, HGH 191AA, Genotropin, Norditropin, Omnitrope, Zomacton, Humatrope
Strong, human-grade evidence
- Regulatory standing. FDA-approved prescription medicine
- Human trials. Backed by controlled human studies
- Registered human trials. 818 registered studies on ClinicalTrials.gov, most advanced Phase 4
- 1 cited source. Includes primary / regulatory sources
Computed with the same four public criteria as every profile. The human-evidence grade on an indexed profile is set automatically and may change when it is hand-reviewed. It is not a safety score, not a purity rating, and not medical advice, and not a claim that this compound treats, cures, or prevents any condition.
What it is
Somatropin is a lab-made version of human growth hormone, a 191 amino acid protein normally produced by the pituitary gland. It acts on growth hormone receptors, largely by raising IGF-1, which influences growth, metabolism, and body composition.
What the evidence shows
Somatropin is FDA approved for conditions such as growth hormone deficiency in children and adults and several other growth disorders, supported by a large body of trials including Phase 4 studies. Use outside approved indications, such as for anti-aging or athletic performance, is not established as safe or effective.
Key facts
Registered human trials
Live from ClinicalTrials.gov, refreshed daily.
Ghrelin, Growth Hormone and Cortisol Interaction in Growth Hormone Deficient Patients
Long-Term Growth and Skeletal Effects of Early Growth Hormone Treatment in Turner Syndrome
Safety, Pharmacokinetics and Pharmacodynamics Study of HL-032 in Healthy Male Volunteers
Evaluation of the Effect of Human Recombinant Growth Hormone in Patients With Advanced Heart Failure
Published literature
Live from Europe PMC. This is how much has been published, not how much is proven in humans.
Intestinal adaptation following resection.
A preliminary study of growth hormone therapy for Crohn's disease.
Humoral regulation of resistin expression in 3T3-L1 and mouse adipose cells.
Safety and Efficacy of Pediatric Growth Hormone Therapy: Results From the Full KIGS Cohort.
Sources
Risks, side effects and study doses are only published on hand-reviewed profiles. Want this one reviewed, or spotted something wrong? Tell us.